职称:讲师

邮箱:shijieland@126.com

电话:022-27893596-215

地址:天津大学灾难医学研究院10号东配楼     

 

个人简介

 

史杰,女,1988年出生,讲师,20196月博士毕业于南开大学生物化学与分子生物学专业。目前主要研究方向为灾难医学领域相关生物材料与组织工程(止血、重要脏器保护)。参与国家级和省部级课题5项,近5年发表论文12篇,其中SCI收录9篇。参与申请发明专利3项。

教育背景

 

2016.9-2019.6 南开大学,生物化学与分子生物学,博士学位

2012.9-2015.6 南开大学,生物化学与分子生物学, 硕士学位2007.9-2011.6 西安工程大学,生物工程,学士学位

研究方向

 

生物材料与组织工程

工作经历

 

2019.7-至今天津大学灾难医学研究院 讲师

2015.7-2016.7 空军军医大学附属医院唐都医院 实习研究员

代表性学术成果

【代表性论文】

l  Jie Shi, Xiangyun Zhang, Li Jiang, Lin Zhang, Yunsheng Dong, Adam C. Midgley, Deling Kong, Shufang Wang*. Regulation of the inflflammatory response by vascular grafts modifified with Aspirin-Triggered Resolvin D1 promotes blood vessel regeneration. J Acta Biomaterialia 97 (2019) 360–373.

l  Jie Shi, Siyuan Chen, Lina Wang, Xiangyun Zhang, Jingchen Gao, Li Jiang, Di Tang, Lin Zhang, Adam Midgley, Deling Kong, Shufang Wang*. Rapid endothelialization and controlled smooth muscle regeneration by electrospun heparin‐loaded polycaprolactone/gelatin hybrid vascular grafts.J Biomed Mater Res B Appl Biomater, 107 (6) (2019), 2040-2049.

l   Xiangyun Zhang, Jie Shi, Siyuan Chen, Yunsheng Dong, Lin Zhang, Adam C Midgley, Deling Kong, Shufang Wang*, Polycaprolactone/gelatin degradable vascular grafts simulating endothelium functions modified by nitric oxide generation. Regenerative medicine. Regenerative Medicine. 2019. DOI  - 10.2217/rme-2019-0015

l Lin Zhang, Yunsheng Dong, Yueming Xue, Jie Shi, Xiangyun Zhang, Yufei Liu, Adam C. Midgley, and Shufang Wang* Multifunctional Triple-Layered Composite Scaffolds Combining Platelet-Rich Fibrin Promote Bone Regeneration.  ACS Biomaterials Science and Engineering. 2019. DOI: 10.1021/acsbiomaterials.9b01022

l Lin Zhang, Yunsheng Dong, Na ZhangJie ShiXiangyun ZhangChunxiao QiAdam MidgleyShufang Wang* Potentials of sandwich-like chitosan/polycaprolactone/gelatin scaffolds for guided tissue regeneration membrane. Materials Science and Engineering C. 2020. DOI:10.1016/j.msec.2019.110618

l  Jiang Li, Gao Jingchen, Song Dongfang, Qiao Mingqiang, Tang Di, Chen Siyuan, Shi Jie, Kong Deling, Wang Shufang*. Electrospun poly(ε-caprolactone) scaffold modified with matrix metalloproteinase for cellularization and vascularization. Journal of Materials Chemistry B, 2018, 6, 2795-2802.

l  Jingchen Gao, Siyuan Chen, Di Tang, Li Jiang, Jie Shi, Shufang Wang*. Mechanical Properties and Degradability of Electrospun PCL/PLGA Blended Scaffolds as Vascular Grafts. Transactions of Tianjin University 2018.4.26. doi.org/10.1007/s12209-018-0152-8.

l Jingchen Gao, Li Jiang, Qinge Liang, Jie Shi, Ding Hou, Di Tang, Siyuan Chen, Deling Kong and Shufang Wang*.The grafts modified by heparinization and catalytic nitric oxide generation used for vascular implantation in rats. Regenerative Biomaterials, 2018, 5(2), 105-114

l  Di Tang, Siyuan Chen, Ding Hou, Jingchen Gao, Li Jiang, Jie Shi, Qinge Liang, Deling Kong, Shufang Wang*. Regulation of macrophage polarization and promotion of endothelialization by NO generating and PEG-YIGSR modified vascular graft. Materials Science and Engineering: C, 2018, 84, 1-11.

l  史杰,沙成花,吴静,孙玥,王淑芳*.全氟十四酸功能化修饰电纺聚己内酯/明胶多孔支架材料制备及评价. 离子交换与吸附. 2019

l 史杰, 唐笛, 高靖辰, 孔德领, 王淑芳*. 巨噬细胞在生物材料植入反应及组织再生中的作用. 生物医学工程学报. 2017, 36(6):749-754

l   唐笛,李岩冬,梁秦阁,姜力,高靖辰,史杰,王淑芳*. 具有NO原位催化能力和内皮细胞特异性粘附的小口径血管支架的制备和表征. 离子交换与吸附. 2017, 33(5):395-402.

l   王淑芳,姜力,史杰.中国发明专利,构建含小分子抗氧化物的人工血管的方法及其应用.201810692170.9,2018.6.29

l   王淑芳,侯丁,史杰,张祥云. 中国发明专利,负载纳豆激酶的小口径人工血管及其制备方法. 201810830187.6, 2018.7.26

l  王淑芳,史杰,王凯,沙成花,吴静,孙玥. 中国发明专利,全氟十四酸修饰的多孔支架材料及其制备方法. 201910166946.8, 2019.304

【主要参与完成科研项目】

1、联勤保障部队战勤部重点项目(BLB19J0062019.6-2021.12380万,在研,参加

2、国防创新项目(c12019090),2019.10-2020.250万,在研,参加

3、国家自然科学基金项目(31870966)利用生物反应器体外培养hiPSCs来源的SMCs构建ECM人工血管,2019.1-2022.1270.8万,在研,参加

4、国家自然科学基金项目(81800931)缓释炎症诱导性外泌体仿生支架促进下颌髁突骨软骨缺损修复及机制研究,2019.1-2021.1221万,在研,参加

5、天津市科技计划项目抗癌重大科技专项(14ZCDZSY00169)新的肝癌标志物抗HBx抗体检测试剂盒的开发,2014.10-2018.275万,完成,参加

【参编教材】

l  中国灾难医学高级教程,参编,华中科技大学出版社,2019

【科技获奖】

 

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